Detalhe da pesquisa
1.
Monoclonal Antibody Aggregation Associated with Free Radical Induced Oxidation.
Int J Mol Sci
; 22(8)2021 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33921206
2.
Light-Induced Covalent Buffer Adducts to Histidine in a Model Protein.
Pharm Res
; 35(3): 67, 2018 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29464419
3.
Photo-oxidation of IgG1 and Model Peptides: Detection and Analysis of Triply Oxidized His and Trp Side Chain Cleavage Products.
Pharm Res
; 34(1): 229-242, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27800571
4.
Degradation Mechanisms of Polysorbate 20 Differentiated by 18O-labeling and Mass Spectrometry.
Pharm Res
; 34(1): 84-100, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738952
5.
Photodegradation Pathways of Protein Disulfides: Human Growth Hormone.
Pharm Res
; 34(12): 2756-2778, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28924868
6.
Photodegradation of human growth hormone: a novel backbone cleavage between Glu-88 and Pro-89.
Mol Pharm
; 10(7): 2693-706, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23721578
7.
Metal-catalyzed oxidation of protein methionine residues in human parathyroid hormone (1-34): formation of homocysteine and a novel methionine-dependent hydrolysis reaction.
Mol Pharm
; 10(2): 739-55, 2013 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23289936
8.
Oxidation of human growth hormone by oxygen-centered radicals: formation of Leu-101 hydroperoxide and Tyr-103 oxidation products.
Mol Pharm
; 9(4): 803-14, 2012 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22397317
9.
Toward understanding molecular heterogeneity of polysorbates by application of liquid chromatography-mass spectrometry with computer-aided data analysis.
Anal Chem
; 83(10): 3934-42, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21491950
10.
Physicochemical stability of the antibody-drug conjugate Trastuzumab-DM1: changes due to modification and conjugation processes.
Bioconjug Chem
; 21(9): 1588-95, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20698491
11.
Vibrational spectroscopy and chemometrics to characterize and quantitate trehalose crystallization.
Anal Biochem
; 399(1): 48-57, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19853571
12.
Characteristics of rhVEGF release from topical hydrogel formulations.
Pharm Res
; 27(4): 644-54, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20155389
13.
Increasing IgG concentration modulates the conformational heterogeneity and bonding network that influence solution properties.
J Phys Chem B
; 113(17): 6109-18, 2009 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19341314
14.
pH dependent effect of glycosylation on protein stability.
Eur J Pharm Sci
; 33(2): 120-7, 2008 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18162379
15.
Dual effects of Tween 80 on protein stability.
Int J Pharm
; 347(1-2): 31-8, 2008 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17692480
16.
Stabilization of a polypeptide in non-aqueous solvents.
Int J Pharm
; 351(1-2): 1-7, 2008 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17964744
17.
The Use of a 2,2'-Azobis (2-Amidinopropane) Dihydrochloride Stress Model as an Indicator of Oxidation Susceptibility for Monoclonal Antibodies.
J Pharm Sci
; 107(2): 550-558, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28989015
18.
The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody.
J Pharm Sci
; 96(7): 1708-18, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17238195
19.
A 2-year follow-up study of alcohol consumption and risk of dementia.
Clin Neurol Neurosurg
; 108(4): 378-83, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16084641
20.
Hydrolysis of Polysorbate 20 and 80 by a Range of Carboxylester Hydrolases.
PDA J Pharm Sci Technol
; 70(4): 332-45, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27020650